Government officials say they are willing to raise the minimum wage from $80 to $100 per month, but union leaders say that is not enough to keep up with inflation.
The protesters blocked a major road in the capital in front of the ministry, and many said they would not stop until their demands are met.
The worker protest coincided with yet another opposition rally at Freedom Park, in the center of Phnom Penh, where opposition protesters are calling for Prime Minister Hun Sen to step down.
Thousands of workers demonstrated in Phnom Penh on Friday, joining with opposition protests that entered their 12th day.
Though the death toll due to traffic accidents in Cambodia is on the rise, experts say it is still relatively low, compared to developed countries.
Thousands of factory workers took their protest to the streets on Thursday and joined the opposition party to demand a pay raise and better working conditions. VOA Khmer Kong Sothanarith has the report.
Cambodian government marked International Anti-Corruption Day with a new commitment to relentlessly crackdown on corruption.
The new floor for prices is $4.50 per minute for calls made within the same network, and $5.95 per minute for calls across different networks.
H&M's new plan will be put into effect next year in one factory in Cambodia and two in Bangladesh.
Cambodia is now Southeast Asia's most corrupt country, surpassing Laos and Burma on Transparency International's annual corruption index.
A major fire has engulfed a paper factory in Phnom Penh, costing the own more than $4 million.